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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDX2 All Species: 15.15
Human Site: T139 Identified Species: 27.78
UniProt: Q99626 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99626 NP_001256.2 313 33510 T139 C A S G L L Q T L N P G P P G
Chimpanzee Pan troglodytes XP_522747 307 33029 F137 C A H N D S C F R G G L P S L
Rhesus Macaque Macaca mulatta XP_001096874 313 33566 T139 C A S G L L Q T L N P G P P G
Dog Lupus familis XP_543154 314 33489 T139 C A T G L L Q T L N P G P P G
Cat Felis silvestris
Mouse Mus musculus P43241 311 33458 T138 C A S G L L Q T L N L G P P G
Rat Rattus norvegicus Q05095 123 14282
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519561 154 17330 C21 F V I S L E G C C H A G G G P
Chicken Gallus gallus Q9DEB6 260 28826 R127 L S P N A Q R R T P Y E W M R
Frog Xenopus laevis Q91622 263 29182 W130 Q R A D P Y E W M R R T G V P
Zebra Danio Brachydanio rerio Q9YGT6 265 29507 S132 T A G S A S K S F G T V L S R
Tiger Blowfish Takifugu rubipres O13074 288 32704 V138 A S T R K D P V V Y P W M K K
Fruit Fly Dros. melanogaster P09085 427 45708 S228 N N N N N S P S T H N N N N N
Honey Bee Apis mellifera XP_001122398 358 40117 N181 G H N S S V S N T N T N V Q H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.8 98.4 96.1 N.A. 92.9 27.1 N.A. 36.7 50.4 47.2 23.9 26.8 27.6 31.5 N.A. N.A.
Protein Similarity: 100 83.7 98.4 97.1 N.A. 94.5 28.7 N.A. 41.2 57.5 58.1 38.9 39.6 38.1 44.4 N.A. N.A.
P-Site Identity: 100 20 100 93.3 N.A. 93.3 0 N.A. 13.3 0 0 6.6 6.6 0 6.6 N.A. N.A.
P-Site Similarity: 100 20 100 100 N.A. 93.3 0 N.A. 20 13.3 20 20 26.6 20 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 47 8 0 16 0 0 0 0 0 8 0 0 0 0 % A
% Cys: 39 0 0 0 0 0 8 8 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 8 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 8 0 0 0 0 8 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % F
% Gly: 8 0 8 31 0 0 8 0 0 16 8 39 16 8 31 % G
% His: 0 8 8 0 0 0 0 0 0 16 0 0 0 0 8 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 0 8 0 0 0 0 0 0 8 8 % K
% Leu: 8 0 0 0 39 31 0 0 31 0 8 8 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 8 8 0 % M
% Asn: 8 8 16 24 8 0 0 8 0 39 8 16 8 8 8 % N
% Pro: 0 0 8 0 8 0 16 0 0 8 31 0 39 31 16 % P
% Gln: 8 0 0 0 0 8 31 0 0 0 0 0 0 8 0 % Q
% Arg: 0 8 0 8 0 0 8 8 8 8 8 0 0 0 16 % R
% Ser: 0 16 24 24 8 24 8 16 0 0 0 0 0 16 0 % S
% Thr: 8 0 16 0 0 0 0 31 24 0 16 8 0 0 0 % T
% Val: 0 8 0 0 0 8 0 8 8 0 0 8 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 8 8 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _